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De nærmest klassiske smertestillende piller som Magnyl, Aspirin, Kodimagnyl og Treo anbefales slet ikke af Sundhedsstyrelsen, da det virksomme stof acetylsalicylsyre ikke virker bedre end paracetamol, Adult men desuden risikerer person voldsommere bivirkninger som mavesår og hovedpine.Smertestillende præparater med det aktive stof acetylsalicyls

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